The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2014
Filed:
Apr. 28, 2006
Shuichi Mizuno, Brookline, MA (US);
Akihiko Kusanagi, Brookline, MA (US);
Laurence J. B. Tarrant, Easthampton, MA (US);
Toshimasa Tokuno, Tokyo, JP;
Robert Lane Smith, Palo Alto, CA (US);
Shuichi Mizuno, Brookline, MA (US);
Akihiko Kusanagi, Brookline, MA (US);
Laurence J. B. Tarrant, Easthampton, MA (US);
Toshimasa Tokuno, Tokyo, JP;
Robert Lane Smith, Palo Alto, CA (US);
Histogenics Corporation, Waltham, MA (US);
Abstract
Neo-cartilage constructs suitable for implantation into a joint cartilage lesion in situ and a method for repair and restoration of function of injured, traumatized, aged or diseased cartilage. The construct comprises at least chondrocytes incorporated into a support matrix processed according to the algorithm comprising variable hydrostatic or atmospheric pressure or non-pressure conditions, variable rate of perfusion, variable medium composition, variable temperature, variable cell density and variable time to which the chondrocytes are subjected.