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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8906679 B1

PDFFull Text
Expired
Date of Patent:
Dec. 09, 2014

Filed:

Apr. 17, 2013

Composite for thermo-sensitive cell-tissue transplanted scaffold and use thereof

Applicant:

Taiepei Veterans General Hospital, Taipei, TW;

Inventors:

Shih-Hwa Chiou, Taipei, TW;

Cherng-Kang Perng, Taipei, TW;

Han-Tzo Lin, Taipei, TW;

Yi-Ping Yang, Taipei, TW;

Assignee:

Taipei Veterans General Hospital, Taipei, TW;

Attorneys:

WPAT, P.C.

Anthony King

Primary Examiner:

Patricia A Leith

Assistant Examiner:

Erin M Bowers

Int. Cl.
CPC ...
A61F 13/00 (2006.01); C12N 5/0775 (2010.01); C12N 5/07 (2010.01); A61K 38/17 (2006.01); A61L 15/32 (2006.01); A61F 2/10 (2006.01); A61L 27/38 (2006.01); A61L 27/50 (2006.01); A61L 27/60 (2006.01); C12N 5/00 (2006.01); A61K 35/12 (2006.01);
U.S. Cl.
CPC ...
A61F 2/105 (2013.01); A61L 27/3834 (2013.01); A61L 27/50 (2013.01); A61L 27/60 (2013.01); C12N 5/0068 (2013.01); A61K 35/12 (2013.01); C12N 2533/52 (2013.01); C12N 2539/10 (2013.01);
Abstract

A composite comprising a stem cell; a biodegradable layer, which can provide an environment for the stem cell to grow and to differentiate, and; a N-isopropylacrylamide (NIPAAm), which can polymerize with the biodegradable layer and possess the temperature-responsive character for easy stripping. The present invention further provides a method for treating a patient with a skin defect, consisting of (a) providing said patient with a composite consisting of a N-isopropylacrylamide (NIPAAm) layer polymerized with a biodegradable layer containing gelatin and a layer of polypropylene (PP) non-woven, wherein a bone marrow derived mononuclear cell with CD45 negative and glycophorin A negative is cultivating on the biodegradable layer; (b) covering said composite on the skin defect of the patient; and (c) treating the composite with water below 25° C. to strip off the layer of polypropylene (PP) non-woven.

Find Patent Forward Citations

Chiou, Shih-Hwa. (2014). Composite for thermo-sensitive cell-tissue transplanted scaffold and use thereof (U.S. Patent No. 8906679). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8906679

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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