The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 09, 2014

Filed:

Nov. 16, 2012
Applicant:

Verenium Corporation, San Diego, CA (US);

Inventors:

David Weiner, San Diego, CA (US);

Ellen Chi, Del Mar, CA (US);

Jennifer Ann Chaplin, San Diego, CA (US);

Aileen Milan, San Diego, CA (US);

Jay M. Short, Del Mar, CA (US);

Grace DeSantis, Del Mar, CA (US);

Mark Madden, San Diego, CA (US);

Mark J. Burk, San Diego, CA (US);

Dan E. Robertson, Belmont, MA (US);

Assignee:

Verenium Corporation, San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/78 (2006.01); C12N 15/00 (2006.01); C12N 1/20 (2006.01); C12N 1/00 (2006.01); C12N 5/00 (2006.01); C12N 1/14 (2006.01); C12P 21/06 (2006.01); C12P 21/04 (2006.01); C07H 21/04 (2006.01); C12P 7/42 (2006.01); C12N 15/81 (2006.01); C12N 15/74 (2006.01); C12N 15/70 (2006.01); C12P 21/00 (2006.01); C12P 13/00 (2006.01); C12P 13/04 (2006.01); C12P 41/00 (2006.01); C12P 7/40 (2006.01);
U.S. Cl.
CPC ...
C12P 7/42 (2013.01); C12N 15/00 (2013.01); C12N 15/815 (2013.01); C12N 15/81 (2013.01); C12N 15/74 (2013.01); C12N 15/70 (2013.01); C12P 21/00 (2013.01); C12N 9/78 (2013.01); C12P 13/004 (2013.01); C12P 13/04 (2013.01); C12P 41/006 (2013.01); C12P 7/40 (2013.01);
Abstract

The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.


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