The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2014
Filed:
May. 10, 2010
Johannes Carolus Clevers, Huis ter Heide, NL;
Nicholas Barker, Utrecht, NL;
Andrea Haegebarth, Berlin, DE;
Marcus Lambertus Van DE Wetering, Houten, NL;
Johannes Carolus Clevers, Huis ter Heide, NL;
Nicholas Barker, Utrecht, NL;
Andrea Haegebarth, Berlin, DE;
Marcus Lambertus Van de Wetering, Houten, NL;
Koninklijke Nederlandse Akademie van Wetenschappen, Utrecht, NL;
Abstract
Described are the use of stem cell markers for the isolation of stem cells and the use of the obtained stem cells in, for example, research or treatment, such as for the preparation of a medicament for the treatment of damaged or diseased tissue. In one aspect, provided is a method for obtaining or isolating stem cells that comprises preparing a cell suspension from a tissue or organ sample, contacting the cell suspension with an Lgr 6 or 5 binding compound, identifying the cells bound to the binding compound, and isolating the stem cells from the binding compound. Further described are methods and compositions for cancer treatment, for example, by eradicating cancer stem cells.