The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2014
Filed:
Jan. 21, 2005
Laurence Rahme, Jamaica Plain, MA (US);
Eric Deziel, Mascouche, CA;
Francois Lepine, Longueuil, CA;
Ronald G. Tompkins, Boston, MA (US);
Gaoping Xiao, New Haven, CT (US);
Laurence Rahme, Jamaica Plain, MA (US);
Eric Deziel, Mascouche, CA;
Francois Lepine, Longueuil, CA;
Ronald G. Tompkins, Boston, MA (US);
Gaoping Xiao, New Haven, CT (US);
The General Hospital Corporation, Boston, MA (US);
Abstract
Disclosed are methods for identifying candidate compounds for treating, reducing, or preventing a pathogenic infection, the methods including: (a) contacting a pathogenic cell with a candidate compound; and (b) measuring the production of a molecule selected from the group consisting of an 4-hydroxy-2-alkylquinoline (HAQ) molecule, 4-hydroxy-2-heptylquinoline (HHQ) molecule, or a derivative or precursor thereof in the cell, a candidate compound that reduces the production relative to production of the molecule by a cell not contacted with the candidate compound, identifying a candidate compound useful for treating, reducing, or preventing a pathogenic infection.