The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2014
Filed:
Mar. 26, 2007
Applicant:
Shaharyar Khan, Charlottesville, VA (US);
Inventor:
Shaharyar Khan, Charlottesville, VA (US);
Assignee:
Gencia Corporation, Charlottsville, VA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/00 (2006.01); A61K 47/44 (2006.01); C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 17/00 (2006.01); G01N 33/53 (2006.01); G01N 33/567 (2006.01); C12N 5/00 (2006.01); C12N 15/88 (2006.01); A61K 38/17 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5008 (2013.01); C12N 2810/00 (2013.01); C12N 15/88 (2013.01); A61K 38/177 (2013.01); C07K 2319/07 (2013.01);
Abstract
Compositions and methods for delivering cargo to cells are provided. One aspect provides a synthetic vesicle containing caveolin 1 or a fragment thereof in an amount effective to form lipid rafts in the vesicle. The synthetic vesicles can be used to deliver polynucleotides, proteins, therapeutic agents, or a combination thereof to specific membrane-bound compartments of a cell. In certain aspects, the synthetic vesicles can deliver cargo to cellular organelles such as mitochondria.