The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 09, 2014

Filed:

Sep. 10, 2010
Applicants:

Peter D. Senter, Seattle, WA (US);

Svetlana O. Doronina, Snohomish, WA (US);

Brian E. Toki, Shoreline, WA (US);

Inventors:

Peter D. Senter, Seattle, WA (US);

Svetlana O. Doronina, Snohomish, WA (US);

Brian E. Toki, Shoreline, WA (US);

Assignee:

Seattle Genetics, Inc., Bothell, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); C07K 5/02 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48246 (2013.01); C07K 5/0205 (2013.01); A61K 47/48269 (2013.01); A61K 47/48569 (2013.01); A61K 47/4863 (2013.01);
Abstract

Drug-Linker-Ligand Conjugates are disclosed in which a Drug is linked to a Ligand via a peptide-based Linker unit. In one embodiment, the Ligand is an Antibody. Drug-Linker compounds and Drug compounds are also disclosed. Methods for treating cancer, an autoimmune disease or an infectious disease using the compounds and compositions of the invention are also disclosed.


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