The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2014
Filed:
Jun. 20, 2012
Ju Young Park, Daejeon, KR;
Wan Jae Myeong, Daejeon, KR;
Bong-sik Jeon, Daejeon, KR;
Eung Gyu Kim, Daejeon, KR;
Eun Byul Kwon, Daejeon, KR;
Taeghwan Hyeon, Seoul, KR;
Daishun Ling, Seoul, KR;
Ju Young Park, Daejeon, KR;
Wan Jae Myeong, Daejeon, KR;
Bong-Sik Jeon, Daejeon, KR;
Eung Gyu Kim, Daejeon, KR;
Eun Byul Kwon, Daejeon, KR;
Taeghwan Hyeon, Seoul, KR;
Daishun Ling, Seoul, KR;
Hanwha Chemical Corporation, Seoul, KR;
Abstract
Provided are a contrast agent for contrast imaging lymph node, which includes iron oxide nanoparticles dispersed and stabilized in an aqueous medium by a mussel adhesive protein-mimetic copolymer, a method for contrast enhanced lymphography using the foregoing contrast agent, and a method for diagnosis of lymph node cancers using the foregoing contrast agent. Using such a mussel adhesive protein-mimetic copolymer, the surface of iron oxide is modified and dispersed well in water to prepare a colloidal solution, which in turn forms the contrast agent containing the colloidal solution. The inventive contrast agent does not have toxicity and is easily taken up to the lymph node to exhibit excellent contrast imaging effects. The contrast agent of the present invention is useful for diagnosis of metastatic cancers.