The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 09, 2014

Filed:

Jul. 01, 2009
Applicants:

Yuichi Tei, Bunkyo-Ku, JP;

Nobuo Sasaki, Bunkyo-Ku, JP;

Shigeki Suzuki, Bunkyo-Ku, JP;

Inventors:

Yuichi Tei, Bunkyo-Ku, JP;

Nobuo Sasaki, Bunkyo-Ku, JP;

Shigeki Suzuki, Bunkyo-Ku, JP;

Assignees:

The University of Tokyo, Tokyo, JP;

Next21 K.K., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/00 (2006.01); A61L 27/50 (2006.01); A61L 27/12 (2006.01);
U.S. Cl.
CPC ...
A61L 27/50 (2013.01); A61L 27/12 (2013.01); A61L 2430/02 (2013.01);
Abstract

Disclosed is an artificial bone material having controlled calcium ion elution, which does not induce cytotoxicity or any inflammatory response. It is found that the elution of a calcium ion from an artificial bone material for transplantation which contains a calcium-containing substance can be prevented effectively by subjecting the carrier to a surface treatment or adding a surface-treating agent to the carrier. It is also found that the induction of cytotoxicity can be prevented and the induction of an inflammatory response can also be prevented by using the above-mentioned carrier having controlled calcium ion elution.


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