The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2014

Filed:

Apr. 16, 2009
Applicants:

Jing Zhu, Beijing, CN;

Zhongyao Yu, Beijing, CN;

Xueling Quan, Beijing, CN;

Guangxin Xiang, Beijing, CN;

Yuming HU, Beijing, CN;

Wanli Xing, Beijing, CN;

Jing Cheng, Beijing, CN;

Inventors:

Jing Zhu, Beijing, CN;

Zhongyao Yu, Beijing, CN;

Xueling Quan, Beijing, CN;

Guangxin Xiang, Beijing, CN;

Yuming Hu, Beijing, CN;

Wanli Xing, Beijing, CN;

Jing Cheng, Beijing, CN;

Assignee:

CapitalBio Corporation, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/00 (2006.01); G01N 33/483 (2006.01);
U.S. Cl.
CPC ...
G01N 33/4836 (2013.01);
Abstract

Among others things, techniques, systems, and apparatus are disclosed for recording electrophysiological signals. In one aspect, a microelectrode sensing device includes a printed circuit board (PCB), a chip unit electrically connected to the PCB, and a cell culture chamber positioned over the chip unit and sealed to the PCB with the chip unit between the PCB and the cell culture chamber. The chip unit includes a substrate; a conductive layer positioned over the substrate that includes one or more recording electrodes; an insulation layer positioned over the conductive layer; another conductive layer positioned over the insulation layer that includes positioning electrodes; and another insulation layer positioned over the other conductive layer. The recording and positioning electrodes are electrically independent so as to independently receive a stimulus signal at each recording electrode and positioning electrode and independently detect a sensed signal at each recording electrode.


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