The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2014

Filed:

Mar. 10, 2011
Applicants:

Akos Vertes, Reston, VA (US);

Jessica A. Stolee, Washington, DC (US);

Bindesh Shrestha, Arlington, VA (US);

Inventors:

Akos Vertes, Reston, VA (US);

Jessica A. Stolee, Washington, DC (US);

Bindesh Shrestha, Arlington, VA (US);

Assignee:

George Washington University, Washington, DC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
H01J 49/00 (2006.01); H01J 49/26 (2006.01); H05H 3/02 (2006.01);
U.S. Cl.
CPC ...
H01J 49/26 (2013.01); H05H 3/02 (2013.01);
Abstract

In various embodiments, a method of laser ablation electrospray ionization mass spectrometry (LAESI-MS) may generally comprise micro-dissecting a cell comprising at least one of a cell wall and a cell membrane to expose at least one subcellular component therein, ablating the at least one subcellular component by an infrared laser pulse to form an ablation plume, intercepting the ablation plume by an electrospray plume to form ions, and detecting the ions by mass spectrometry.


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