The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2014

Filed:

Oct. 16, 2009
Applicants:

Gilles Chambournier, Ann Arbor, MI (US);

Andriy Kornilov, Ypsilanti, MI (US);

Hussein M. Mahmoud, Ann Arbor, MI (US);

Ivan Vesely, Neratovice, CZ;

Stephen D. Barrett, Hartland, MI (US);

Inventors:

Gilles Chambournier, Ann Arbor, MI (US);

Andriy Kornilov, Ypsilanti, MI (US);

Hussein M. Mahmoud, Ann Arbor, MI (US);

Ivan Vesely, Neratovice, CZ;

Stephen D. Barrett, Hartland, MI (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 405/00 (2006.01); C07D 307/935 (2006.01);
U.S. Cl.
CPC ...
C07D 307/935 (2013.01);
Abstract

A process for the synthesis and purification of F-series prostaglandin compounds and synthetic intermediates used to prepare them. The synthetic intermediates are solid and may be purified by precipitation and therefore may form the representative F-series prostaglandin compounds such as latanoprost, bimatoprost, fluprostenol, cloprostenol, and substituted analogs therefrom in highly pure forms.


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