The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2014

Filed:

Jul. 16, 2012
Applicants:

Weiwen Ying, Ayer, MA (US);

David James, Cambridge, MA (US);

Shijie Zhang, Nashua, NH (US);

Teresa Przewloka, Tewksbury, MA (US);

Junghyun Chae, Arlington, MA (US);

Dinesh U. Chimmanamada, Waltham, MA (US);

Chi-wan Lee, Grafton, MA (US);

Elena Kostik, Arlington, MA (US);

Howard P. NG, Belmont, MA (US);

Kevin Foley, Cambridge, MA (US);

Zhenjian Du, Northborough, MA (US);

James Barsoum, Lexington, MA (US);

Inventors:

Weiwen Ying, Ayer, MA (US);

David James, Cambridge, MA (US);

Shijie Zhang, Nashua, NH (US);

Teresa Przewloka, Tewksbury, MA (US);

Junghyun Chae, Arlington, MA (US);

Dinesh U. Chimmanamada, Waltham, MA (US);

Chi-Wan Lee, Grafton, MA (US);

Elena Kostik, Arlington, MA (US);

Howard P. Ng, Belmont, MA (US);

Kevin Foley, Cambridge, MA (US);

Zhenjian Du, Northborough, MA (US);

James Barsoum, Lexington, MA (US);

Assignee:

Synta Pharmaceuticals Corp., Lexington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 405/04 (2006.01); C07D 417/04 (2006.01); C07D 413/04 (2006.01); C07D 403/04 (2006.01); C07D 403/10 (2006.01); C07D 249/08 (2006.01); C07D 473/00 (2006.01); C07D 249/12 (2006.01); C07D 409/04 (2006.01); C07D 473/34 (2006.01);
U.S. Cl.
CPC ...
C07D 249/08 (2013.01); C07D 413/04 (2013.01); C07D 403/04 (2013.01); C07D 403/10 (2013.01); C07D 401/04 (2013.01); C07D 405/04 (2013.01); C07D 473/00 (2013.01); C07D 249/12 (2013.01); C07D 409/04 (2013.01); C07D 417/04 (2013.01); C07D 473/34 (2013.01);
Abstract

The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.


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