The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 2014
Filed:
Apr. 20, 2012
Carmen M. Baldino, Woburn, MA (US);
Justin L. Caserta, Billerica, MA (US);
Stephane A. Dumas, Cambridge, MA (US);
Chee-seng Lee, Somerville, MA (US);
Yvonne L. Flanders, Medford, MA (US);
Carmen M. Baldino, Woburn, MA (US);
Justin L. Caserta, Billerica, MA (US);
Stephane A. Dumas, Cambridge, MA (US);
Chee-Seng Lee, Somerville, MA (US);
Yvonne L. Flanders, Medford, MA (US);
Jasco Pharmaceuticals, LLC, Woburn, MA (US);
Abstract
Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim-1, Pim-2, Pim-3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim-1, Pim-2, Pim-3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway.