The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2014

Filed:

Dec. 13, 2010
Applicants:

Mart Saarma, Helsinki, FI;

Mati Karelson, Vahi, EE;

Maxim Bespalov, Helsinki, FI;

Mehis Pilv, Tallinn, EE;

Inventors:

Mart Saarma, Helsinki, FI;

Mati Karelson, Vahi, EE;

Maxim Bespalov, Helsinki, FI;

Mehis Pilv, Tallinn, EE;

Assignee:

GeneCode AS, Tallinn, EE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); C07D 241/04 (2006.01); C07D 295/192 (2006.01); C07D 215/46 (2006.01); C07D 285/135 (2006.01); C07D 513/10 (2006.01); C07D 219/10 (2006.01); C07D 263/57 (2006.01);
U.S. Cl.
CPC ...
C07D 215/46 (2013.01); C07D 295/192 (2013.01); C07D 285/135 (2013.01); C07D 513/10 (2013.01); C07D 219/10 (2013.01); C07D 263/57 (2013.01);
Abstract

Disclosed are compounds and methods for treating neurological and other disorders by administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for GFRα receptor molecules, which can be mimetics of glial-derived neurotrophic factor (GDNF) family ligands (GFLs), GFRα/RET signaling pathway agonists, and/or direct RET agonists (activators).


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