The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 2014
Filed:
Nov. 08, 2011
Jiang Chang, Beijing, CN;
Kun Liu, Edison, NJ (US);
Ernest J. Mceachern, Vancouver, CA;
Changwei Mu, Beijing, CN;
Harold G. Selnick, Ambler, PA (US);
Feng Shi, Beijing, CN;
David J. Vocadlo, Burnaby, CA;
Yaode Wang, Beijing, CN;
Zhongyong Wei, Beijing, CN;
Yuanxi Zhou, Richmond, CA;
Yongbao Zhu, Langley, CA;
Jiang Chang, Beijing, CN;
Kun Liu, Edison, NJ (US);
Ernest J. McEachern, Vancouver, CA;
Changwei Mu, Beijing, CN;
Harold G. Selnick, Ambler, PA (US);
Feng Shi, Beijing, CN;
David J. Vocadlo, Burnaby, CA;
Yaode Wang, Beijing, CN;
Zhongyong Wei, Beijing, CN;
Yuanxi Zhou, Richmond, CA;
Yongbao Zhu, Langley, CA;
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The invention is directed to compounds for selectively inhibiting glycosidases, uses of the compounds and pharmaceutical compositions including the compounds, and methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, and/or accumulation or deficiency of O-GlcNAc.