The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2014

Filed:

Aug. 11, 2010
Applicants:

Adel Rafai Far, Ville Mont-Royal, CA;

Kelly Tanaka, Toronto, CA;

Evelyne Dietrich, Laval, CA;

Ranga Reddy, Hyderabad, IN;

Ting Kang, Kirkland, CA;

Inventors:

Adel Rafai Far, Ville Mont-Royal, CA;

Kelly Tanaka, Toronto, CA;

Evelyne Dietrich, Laval, CA;

Ranga Reddy, Hyderabad, IN;

Ting Kang, Kirkland, CA;

Assignee:

The Medicines Company, Parsippany, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 5/12 (2006.01); A61K 38/12 (2006.01); A61K 38/14 (2006.01); A61P 31/04 (2006.01); A61K 47/48 (2006.01); C07K 9/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 9/008 (2013.01); A61K 47/48046 (2013.01); A61K 38/12 (2013.01); A61K 38/14 (2013.01); A61K 45/06 (2013.01); A61K 47/48038 (2013.01); A61K 47/48215 (2013.01);
Abstract

The invention relates to derivatives of glycopeptide and lipoglycopeptide antibiotics possessing an altered ionization state with respect to the parent glycopeptide or lipoglycopeptide antibiotic, and having the ability to be regenerated as the parent glycopeptide or lipoglycopeptide antibiotic under physiological conditions. These compounds are useful as antibiotics for the prevention and/or the treatment of bacterial infections.


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