The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2014

Filed:

Nov. 23, 2006
Applicants:

Jacques Henri Max Cohen, Reims, FR;

Wael Mahmoud, Reims, FR;

Marcelle Tonye Libyh, Reims, FR;

Nathalie Godin, Reims, FR;

Annelise Gimenez, Chalons en Champangne, FR;

Thierry Tabary, Reims, FR;

Beatrice Donvito, Reims, FR;

Daniel Baty, Marseille, FR;

Xavier Dervillez, Wincheringen, DE;

Inventors:

Jacques Henri Max Cohen, Reims, FR;

Wael Mahmoud, Reims, FR;

Marcelle Tonye Libyh, Reims, FR;

Nathalie Godin, Reims, FR;

Annelise Gimenez, Chalons en Champangne, FR;

Thierry Tabary, Reims, FR;

Beatrice Donvito, Reims, FR;

Daniel Baty, Marseille, FR;

Xavier Dervillez, Wincheringen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/08 (2006.01); C07K 16/46 (2006.01); C07K 16/30 (2006.01); C07K 16/28 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48261 (2013.01); C07K 2319/01 (2013.01); C07K 16/2896 (2013.01); C07K 16/3007 (2013.01); C07K 2317/22 (2013.01); C07K 2317/34 (2013.01); C07K 2317/622 (2013.01); C07K 2317/569 (2013.01); C07K 2319/00 (2013.01); C07K 2319/40 (2013.01); C07K 2319/735 (2013.01); A61K 47/48561 (2013.01); A61K 47/4833 (2013.01); A61K 47/48576 (2013.01);
Abstract

The invention relates to a protein construct, comprising (i) a targeting moiety that is capable of binding to a target cell, and (ii) an effector immunogenic moiety that is capable of triggering an existing, vaccine-induced or natural, immune response. The protein construct, that is preferably in the form of a heteromultimeric protein, is useful for redirecting an immune response that was pre-existing in a patient, toward an undesired target cell.


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