The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2014

Filed:

Apr. 22, 2013
Applicant:

Kyowa Hakko Kirin Co., Ltd., Chiyoda-ku, Tokyo, JP;

Inventors:

Kenya Shitara, Machida, JP;

Kazuyasu Nakamura, Machida, JP;

Emi Hosaka, Machida, JP;

Akiko Shimizu, Machida, JP;

Masamichi Koike, Machida, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); G01N 33/68 (2006.01); C07K 14/715 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2866 (2013.01); C07K 2317/732 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); G01N 2333/4719 (2013.01); A61K 2039/505 (2013.01); G01N 33/6863 (2013.01); C07K 14/7158 (2013.01);
Abstract

A human CDR-grafted antibody or the antibody fragment thereof which specifically reacts with the extracellular region of human CC chemokine receptor 4 (CCR4) but does not react with a human blood platelet; a human CDR-grafted antibody or the antibody fragment thereof which specifically reacts with the extracellular region of CCR4 and has a cytotoxic activity against a CCR4-expressing cell; and a medicament, a therapeutic agent or a diagnostic agent comprising at least one of the antibodies and the antibody fragments thereof as an active ingredient.


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