The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 2014
Filed:
Nov. 02, 2009
Applicants:
Scott A. Hilderbrand, Swampscott, MA (US);
Neal K. Devaraj, Boston, MA (US);
Ralph Weissleder, Charlestown, MA (US);
Inventors:
Scott A. Hilderbrand, Swampscott, MA (US);
Neal K. Devaraj, Boston, MA (US);
Ralph Weissleder, Charlestown, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61K 51/04 (2006.01); B82Y 5/00 (2011.01); A61K 49/00 (2006.01); A61K 47/48 (2006.01); G01N 33/532 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5306 (2013.01); A61K 51/0474 (2013.01); B82Y 5/00 (2013.01); A61K 49/0041 (2013.01); A61K 49/0019 (2013.01); A61K 47/4813 (2013.01); G01N 33/532 (2013.01); A61K 51/0495 (2013.01); A61K 47/48746 (2013.01);
Abstract
The present application provides compositions and methods using bioorthogonal inverse electron demand Diels-Alder cycloaddition reaction for rapid and specific covalent delivery of a 'payload' to a ligand bound to a biological target.