The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 2014
Filed:
Apr. 27, 2012
Kashan Ali Shaikh, Clifton Park, NY (US);
Jessica Marie Godin, Niskayuna, NY (US);
Alex David Corwin, Niskayuna, NY (US);
Robert John Filkins, Niskayuna, NY (US);
Kashan Ali Shaikh, Clifton Park, NY (US);
Jessica Marie Godin, Niskayuna, NY (US);
Alex David Corwin, Niskayuna, NY (US);
Robert John Filkins, Niskayuna, NY (US);
General Electric Company, Niskayuna, NY (US);
Abstract
A microfluidic flow cell subassembly, which may be assembled into a flow cell having fluidic connections outside of the main substrate, is described for encapsulating a sample to allow for subsequent controlled delivery of reagents to the sample, such as multiplexed in situ biomarker staining and analysis. Methods for fabricating the subassembly and assembled flow cell are also provided. The method includes the steps of adhering a gasket layer to a substrate layer, wherein the gasket layer may contain enclosed features and adhering an adherent layer to the gasket layer. The subassembly may be sealed against a solid support to form a flow cell.