The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2014

Filed:

Nov. 28, 2011
Applicants:

Gabriel Nestor Sanchez, Stanford, CA (US);

Scott L. Delp, Stanford, CA (US);

Mark J. Schnitzer, Palo Alto, CA (US);

Michael E. Llewellyn, Palo Alto, CA (US);

Inventors:

Gabriel Nestor Sanchez, Stanford, CA (US);

Scott L. Delp, Stanford, CA (US);

Mark J. Schnitzer, Palo Alto, CA (US);

Michael E. Llewellyn, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 6/00 (2006.01); A61B 5/00 (2006.01); G01N 21/64 (2006.01); A61B 1/04 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0062 (2013.01); A61B 5/0086 (2013.01); A61B 5/4519 (2013.01); A61B 5/726 (2013.01); A61B 5/4528 (2013.01); G01N 21/6458 (2013.01); A61B 5/0068 (2013.01); A61B 5/0084 (2013.01); A61B 5/0071 (2013.01); A61B 5/6848 (2013.01); A61B 5/7207 (2013.01); A61B 1/043 (2013.01);
Abstract

Biological tissue such as skeletal and cardiac muscle can be imaged by using an objective-based probe in the tissue and scanning at a sufficiently fast rate to mitigate motion artifacts due to physiological motion. According to one example embodiment, such a probe is part of a system that is capable of reverse-direction high-resolution imaging without needing to stain or otherwise introduce a foreign element used to generate or otherwise increase the sensed light. The probe can include a light generator for generating light pulses that are directed towards structures located within the thick tissue. The system can additionally include aspects that lessen adverse image-quality degradation. Further, the system can additionally be constructed as a hand-held device.


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