The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2014

Filed:

Aug. 29, 2011
Applicants:

Vimal Kumar Shrawat, Karnataka, IN;

Karri Papa Rao, Karnataka, IN;

Rafiuddin, Karnataka, IN;

Prashant Purohit, Karnataka, IN;

Inventors:

Vimal Kumar Shrawat, Karnataka, IN;

Karri Papa Rao, Karnataka, IN;

Rafiuddin, Karnataka, IN;

Prashant Purohit, Karnataka, IN;

Assignee:

Shilpa Medicare Limited, Raichur, Karnataka, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 381/00 (2006.01); C07C 255/50 (2006.01); C07C 253/30 (2006.01); C07C 315/02 (2006.01); C07C 253/34 (2006.01);
U.S. Cl.
CPC ...
C07C 253/30 (2013.01); C07C 315/02 (2013.01); C07C 253/34 (2013.01);
Abstract

The present invention provide processes for the preparation of N-[4-Cyano-3-(trifluoro methyl)phenyl]-3-[(4-fluorophenyl)sulphonyl]-2-hydroxy-2-methyl propanamide (I). The present application also provides a method of purification of N-[4-Cyano-3-(trifluoro methyl)phenyl]-3-[(4-fluorophenyl)sulphonyl]-2-hydroxy-2-methyl propanamide (I) using ethyl acetate solvent resulting in the product, substantially free from process related impurities A, B, C and D. The crystalline product of the process according to the present invention having an XRDP pattern as per FIG., is useful as an active pharmaceutical and has anti-androgenic activity.


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