The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2014
Filed:
Jan. 13, 2014
Applicant:
Nektar Therapeutics, San Francisco, CA (US);
Inventors:
Samuel P. McManus, Guntersville, AL (US);
Antoni Kozlowski, Huntsville, AL (US);
Tracy L. Hutchison, New Market, AL (US);
Brian Bray, Huntsville, AL (US);
Xiaoming Shen, Millbrae, CA (US);
Assignee:
Nektar Therapeutics, San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/46 (2006.01); C07D 403/12 (2006.01); A61K 47/48 (2006.01); C08G 65/333 (2006.01); C08G 69/08 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 47/48215 (2013.01); C08G 65/33337 (2013.01); C08G 69/08 (2013.01);
Abstract
Methods for forming maleimide functionalized polymers are provided. In one such embodiment, a maleimide functionalized polymer is prepared in a method that includes a step of carrying out a reverse Diels-Alder reaction. Intermediates useful in the methods, as well as methods for preparing the intermediates, are also provided. Also provided are polymeric reagents, methods of using polymeric reagents, compounds and conjugates.