The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2014

Filed:

Jan. 25, 2012
Applicants:

Miroslav Terinek, Muenchwilen, CH;

Dominik Faber, Muenchwilen, CH;

Stefan Koenig, Muenchwilen, CH;

Inventors:

Miroslav Terinek, Muenchwilen, CH;

Dominik Faber, Muenchwilen, CH;

Stefan Koenig, Muenchwilen, CH;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/14 (2006.01); C07C 251/56 (2006.01); C07C 329/04 (2006.01); C07C 231/14 (2006.01); C07C 329/02 (2006.01); C07C 251/64 (2006.01);
U.S. Cl.
CPC ...
C07C 231/14 (2013.01); C07C 329/04 (2013.01); C07C 251/56 (2013.01); C07C 329/02 (2013.01); C07C 251/64 (2013.01); C07C 2103/66 (2013.01);
Abstract

The invention relates to a process for the preparation of 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-yl)-amide by acylating the oxime oxygen of the compound of formula (VIII), in the presence of a solvent and an acylating agent of formula (XI) RC(X)—CI (XI); wherein X is oxygen or sulfur; Ris chloro if X is oxygen or sulfur; or R1 is C-Calkoxy, CH—C(═CH)—O—, phenoxy or trichloromethoxy if X is oxygen; and a) if Ris chloro and the compound of formula (XI) was added to the compound of formula (VIII); reacting the so obtained product of formula (XIIa) wherein X is oxygen or sulfur; with the compound of formula (IX) b) if Ris chloro and the compound of formula (VIII) was added to the compound of formula (XI); or Ris C-Calkoxy, CH—C(═CH)—O—, phenoxy or trichloromethoxy if X is oxygen; reacting the so obtained product of formula (XII) wherein X is oxygen or sulfur; Ris chloro if X is oxygen or sulfur; or Ris C-Calkoxy, CH—C(═CH)—O—, phenoxy or trichloromethoxy if X is oxygen; with the compound of formula (IX).


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