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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8895755 B1

PDFFull Text
Date of Patent:
Nov. 25, 2014

Filed:

Sep. 24, 2013

Intermediates for preparing dual-acting benzyl triazole antihypertensive agents having angiotensin ii type i receptor antagonist activity and neprilysin-inhibition activity

Applicants:

Paul Allegretti, Fort Collins, CO (US);

Seok-ki Choi, Ann Arbor, MI (US);

Roland Gendron, San Francisco, CA (US);

Paul R. Fatheree, San Francisco, CA (US);

Keith Jendza, Boston, MA (US);

Robert Murray Mckinnell, Millbrae, CA (US);

Darren Mcmurtrie, Foster City, CA (US);

Brooke Olson, Williamstown, MA (US);

Inventors:

Paul Allegretti, Fort Collins, CO (US);

Seok-Ki Choi, Ann Arbor, MI (US);

Roland Gendron, San Francisco, CA (US);

Paul R. Fatheree, San Francisco, CA (US);

Keith Jendza, Boston, MA (US);

Robert Murray McKinnell, Millbrae, CA (US);

Darren McMurtrie, Foster City, CA (US);

Brooke Olson, Williamstown, MA (US);

Assignee:

Theravance Biopharma R&D IP, LLC, South San Francisco, CA (US);

Attorneys:

Jeffrey A. Hagenah

Shelley Eberle

Primary Examiner:

Kristin Vajda

Assistant Examiner:

Valerie Rodriguez-Garcia

Int. Cl.
CPC ...
C07D 249/08 (2006.01); C07D 513/04 (2006.01); C07D 213/89 (2006.01); C07D 233/64 (2006.01); C07D 233/70 (2006.01); A61K 31/4188 (2006.01); C07D 233/68 (2006.01); C07D 513/14 (2006.01); C07D 231/14 (2006.01); C07D 233/90 (2006.01); A61K 31/4196 (2006.01); C07D 403/10 (2006.01); C07D 401/12 (2006.01); C07D 213/64 (2006.01); C07D 207/46 (2006.01); A61K 45/00 (2006.01); C07D 255/02 (2006.01); A61K 31/415 (2006.01); A61K 31/4412 (2006.01); A61K 31/417 (2006.01);
U.S. Cl.
CPC ...
C07D 213/89 (2013.01); C07D 513/04 (2013.01); C07D 233/64 (2013.01); C07D 233/70 (2013.01); A61K 31/4188 (2013.01); C07D 233/68 (2013.01); C07D 513/14 (2013.01); C07D 231/14 (2013.01); C07D 233/90 (2013.01); A61K 31/4196 (2013.01); C07D 403/10 (2013.01); C07D 401/12 (2013.01); C07D 213/64 (2013.01); C07D 207/46 (2013.01); A61K 45/00 (2013.01); C07D 249/08 (2013.01); C07D 255/02 (2013.01); A61K 31/415 (2013.01); A61K 31/4412 (2013.01); A61K 31/417 (2013.01);
Abstract

The invention is directed to intermediates for preparing compounds having the formula:

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