The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2014

Filed:

Dec. 20, 2012
Applicant:

Koninklijke Nederlandse Akademie Van Wetenschappen, Amsterdam, NL;

Inventors:

Ronald H. A. Plasterk, Bussum, NL;

Eugene Berezikov, Vleuten, NL;

Edwin Pieter Cuppen, Utrecht, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12Q 2600/158 (2013.01); C12N 2310/141 (2013.01); C12Q 2600/178 (2013.01); C12N 2320/10 (2013.01); C12Q 1/6886 (2013.01);
Abstract

The invention provides a method for characterising a sample comprising nucleic acid derived from a cell. The method comprises determining whether a sample comprises at least a minimal sequence of at least one new microRNA (miRNA) according to the invention or a mammalian ortholog thereof and characterizing the sample on the basis of the presence or absence of the miRNA. The invention further provides nucleic acid molecules and collections thereof and their use in therapeutic and diagnostic applications. The invention furthermore provides a method for identifying a miRNA molecule or a precursor molecule thereof.


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