The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2014
Filed:
Jan. 04, 2011
Carina Engstrand, Uppsala, SE;
Annika Forss, Uppsala, SE;
Gunnar Glad, Uppsala, SE;
Bo-lennart Johansson, Uppsala, SE;
Hans J. Johansson, Uppsala, SE;
Jean-luc Maloisel, Uppsala, SE;
Carina Engstrand, Uppsala, SE;
Annika Forss, Uppsala, SE;
Gunnar Glad, Uppsala, SE;
Bo-Lennart Johansson, Uppsala, SE;
Hans J. Johansson, Uppsala, SE;
Jean-Luc Maloisel, Uppsala, SE;
GE Healthcare Bio-Sciences AB, Uppsala, SE;
Abstract
The present invention relates to a chromatography ligand defined by the following formula R—R—N(R)—R—Rwherein Ris a substituted or non-substituted phenyl group; Ris a hydrocarbon chain comprising 0-4 carbon atoms; Ris a hydrocarbon chain comprising 1-3 carbon atoms; Ris a hydrocarbon chain comprising 1-5 carbon atoms; and Ris OH or H. The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies.