The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2014
Filed:
May. 03, 2010
Maggie Joyce Rathos, Mumbai, IN;
Kalpana Sanjay Joshi, Mumbai, IN;
Nikhil Krishnamurthy Hebbar, Mumbai, IN;
Somesh Sharma, Mumbai, IN;
Maggie Joyce Rathos, Mumbai, IN;
Kalpana Sanjay Joshi, Mumbai, IN;
Nikhil Krishnamurthy Hebbar, Mumbai, IN;
Somesh Sharma, Mumbai, IN;
Piramal Enterprises Limited, Mumbai, IN;
Abstract
The present invention relates to a combination for the treatment of cancer wherein the combination exhibits a synergistic effect. The combination comprises radiation and at least one cyclin dependent kinase (CDK) inhibitor selected from the compounds of formula I or a pharmaceutically acceptable salt or a solvate thereof. The present invention also relates to a method for the treatment of cancer, which method comprises administering to a patient in need of such a treatment, a therapeutically effective amount of the combination. The present invention also relates to the use of a CDK inhibitor selected from the compounds of formula I as a radiosensitizer that enhances the efficacy of radiotherapy for the treatment of cancer, particularly head and neck cancer.