The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2014
Filed:
Jun. 25, 2012
Itzia Arroyo, Union, NJ (US);
Davida Krueger, Brooklyn, NY (US);
Ping Chen, Edison, NJ (US);
Aaron Moment, Middletown, NJ (US);
Tesfaye Biftu, Freehold, NJ (US);
Faye Sheen, Hoddesdon, GB;
Yanfeng Zhang, Panan, CN;
Itzia Arroyo, Union, NJ (US);
Davida Krueger, Brooklyn, NY (US);
Ping Chen, Edison, NJ (US);
Aaron Moment, Middletown, NJ (US);
Tesfaye Biftu, Freehold, NJ (US);
Faye Sheen, Hoddesdon, GB;
Yanfeng Zhang, Panan, CN;
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Merck Sharp & Dohme Ltd., Hoddesdon, GB;
Abstract
Novel crystalline forms of (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine are potent inhibitors of dipeptidyl peptidase-IV and are useful for the treatment of non-insulin dependent (Type 2) diabetes mellitus. The invention also relates to pharmaceutical compositions containing these novel forms, processes to prepare these forms and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes.