The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2014
Filed:
Aug. 09, 2012
Applicants:
Maurizio Botta, Siena, IT;
Valentina Corradi, San Rocco-Roverè V.se, IT;
Federico Falchi, Monterotondo Marittimo, IT;
Manuela Mancini, Bologna, IT;
Maria Alessandra Santucci, Bologna, IT;
Inventors:
Maurizio Botta, Siena, IT;
Valentina Corradi, San Rocco-Roverè V.se, IT;
Federico Falchi, Monterotondo Marittimo, IT;
Manuela Mancini, Bologna, IT;
Maria Alessandra Santucci, Bologna, IT;
Assignee:
Università degli Studi di Siena, Siena, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/56 (2006.01); A61K 31/415 (2006.01); C07D 401/00 (2006.01); C12Q 1/48 (2006.01); G01N 33/573 (2006.01); A61K 31/4152 (2006.01); G01N 33/574 (2006.01); A61K 31/4035 (2006.01); A61K 31/196 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4152 (2013.01); C12Q 1/485 (2013.01); G01N 33/573 (2013.01); G01N 33/57426 (2013.01); A61K 31/4035 (2013.01); A61K 31/196 (2013.01);
Abstract
The present invention refers to compounds with inhibitory activity against 14-3-3 proteins and their use in the treatment of tumors, in particular chronic myeloid leukemia. The invention also provides methods for the identification of 14-3-3 protein inhibitors.