The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2014
Filed:
Dec. 28, 2012
Hideyasu Fujiwara, Ashigarakami-gun, JP;
Kimihiko Sato, Ashigarakami-gun, JP;
Shinsuke Mizumoto, Ashigarakami-gun, JP;
Yuichiro Sato, Toyama, JP;
Hideki Kurihara, Ashigarakami-gun, JP;
Yohei Kubo, Ashigarakami-gun, JP;
Hiyoku Nakata, Ashigarakami-gun, JP;
Yasutaka Baba, Ashigarakami-gun, JP;
Takashi Tamura, Ashigarakami-gun, JP;
Hidenobu Kuniyoshi, Ashigarakami-gun, JP;
Shinji Hagiwara, Ashigarakami-gun, JP;
Mari Yamamoto, Toyama, JP;
Hideyasu Fujiwara, Ashigarakami-gun, JP;
Kimihiko Sato, Ashigarakami-gun, JP;
Shinsuke Mizumoto, Ashigarakami-gun, JP;
Yuichiro Sato, Toyama, JP;
Hideki Kurihara, Ashigarakami-gun, JP;
Yohei Kubo, Ashigarakami-gun, JP;
Hiyoku Nakata, Ashigarakami-gun, JP;
Yasutaka Baba, Ashigarakami-gun, JP;
Takashi Tamura, Ashigarakami-gun, JP;
Hidenobu Kuniyoshi, Ashigarakami-gun, JP;
Shinji Hagiwara, Ashigarakami-gun, JP;
Mari Yamamoto, Toyama, JP;
FUJIFILM Corporation, Tokyo, JP;
Abstract
An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. The present invention provides a nicotinamide derivative represented by the following formula (I) (wherein Rrepresents a halogen atom; Rrepresents a Calkyl group, a Calkenyl group, a Calkynyl group, a Ccycloalkyl group, an aryl group, an ar-Calkyl group or a heterocyclic group, each optionally having at least one substituent; Rrepresents an aryl group or a heterocyclic group each optionally having at least one substituent; and Rand Reach independently represent a hydrogen atom; and Rand Rmay form a cyclic amino group optionally having at least one substituent together with the nitrogen atom to which they bind) or a salt thereof, and a pharmaceutical composition for use in the treatment of a Syk-related disease which comprises the nicotinamide derivative or a salt thereof.