The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2014
Filed:
Oct. 14, 2013
Applicant:
Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);
Inventors:
Ihab S. Darwish, San Carlos, CA (US);
Jiaxin Yu, Foster City, CA (US);
Hui Hong, Palo Alto, CA (US);
Rajinder Singh, Belmont, CA (US);
Sambaiah Thota, Fremont, CA (US);
Xiang Xu, Foster City, CA (US);
Assignee:
Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); A61K 31/437 (2006.01); C07D 471/04 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01); C07D 401/12 (2013.01);
Abstract
Disclosed are carboxamide, sulfonamide and amine compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure in which R, R, R, D, E, J, T, p, q and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.