The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2014
Filed:
Jul. 29, 2009
Applicants:
José Manuel Bartolomé-nebreda, Toledo, ES;
Gregor James Macdonald, Zoersel, BE;
Michiel Luc Maria Van Gool, Madrid, ES;
Inventors:
José Manuel Bartolomé-Nebreda, Toledo, ES;
Gregor James MacDonald, Zoersel, BE;
Michiel Luc Maria Van Gool, Madrid, ES;
Assignee:
Janssen Pharmaceutica NV, Beerse, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/74 (2006.01); C07D 213/84 (2006.01); C07D 401/04 (2006.01); C07D 409/04 (2006.01);
U.S. Cl.
CPC ...
C07D 213/74 (2013.01); C07D 213/84 (2013.01);
Abstract
The present invention relates to piperazin-1-yl-trifluoromethyl-substituted-pyridines that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds find utility as medicines for treating or preventing central nervous system disorders, for example schizophrenia, by exerting an antipsychotic effect without motor side effects.