The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2014
Filed:
Oct. 01, 2013
Applicant:
Proteotech Inc, Kirkland, WA (US);
Inventors:
Alan D. Snow, Lynnwood, WA (US);
Beth Nguyen, Trophy Club, TX (US);
Gerardo Castillo, Bothell, WA (US);
Virginia Sanders, San Francisco, CA (US);
Thomas Lake, Snohomish, WA (US);
Assignee:
ProteoTech Inc, Kirkland, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/58 (2006.01); A61K 31/50 (2006.01); A61K 31/497 (2006.01); A01N 43/40 (2006.01); A61K 31/435 (2006.01); C07D 317/54 (2006.01); C07D 263/38 (2006.01); C07D 231/06 (2006.01); C07D 317/66 (2006.01); C07D 295/192 (2006.01); C07D 317/58 (2006.01); C07D 487/08 (2006.01); C07D 265/38 (2006.01); C07D 207/16 (2006.01); C07D 407/14 (2006.01); C07D 451/06 (2006.01); C07C 69/017 (2006.01); C07C 235/56 (2006.01); C07D 413/14 (2006.01); C07C 45/64 (2006.01); C07C 237/22 (2006.01); C07D 405/14 (2006.01); C07C 39/17 (2006.01); C07D 317/68 (2006.01); C07D 491/08 (2006.01); C07D 317/50 (2006.01); C07C 39/15 (2006.01); C07C 49/248 (2006.01); C07C 235/34 (2006.01); C07C 231/02 (2006.01); C07D 471/04 (2006.01); C07D 211/74 (2006.01); C07C 39/16 (2006.01); C07C 49/835 (2006.01); C07C 275/34 (2006.01); C07C 49/83 (2006.01); C07C 235/48 (2006.01); C07D 213/69 (2006.01); C07D 409/14 (2006.01); C07C 235/54 (2006.01); C07D 333/16 (2006.01); C07D 241/08 (2006.01); C07C 215/50 (2006.01); C07D 317/60 (2006.01); C07D 221/18 (2006.01); C07D 311/60 (2006.01); C07C 235/38 (2006.01); C07D 295/096 (2006.01); C07C 45/62 (2006.01); C07D 213/85 (2006.01); C07D 213/30 (2006.01); C07D 221/08 (2006.01);
U.S. Cl.
CPC ...
C07C 49/248 (2013.01); C07D 317/54 (2013.01); C07D 263/38 (2013.01); C07D 231/06 (2013.01); C07D 317/66 (2013.01); C07D 295/192 (2013.01); C07D 317/58 (2013.01); C07D 487/08 (2013.01); C07D 265/38 (2013.01); C07D 207/16 (2013.01); C07D 407/14 (2013.01); C07D 451/06 (2013.01); C07C 69/017 (2013.01); C07C 235/56 (2013.01); C07D 413/14 (2013.01); C07C 45/64 (2013.01); C07C 237/22 (2013.01); C07D 405/14 (2013.01); C07C 39/17 (2013.01); C07D 317/68 (2013.01); C07D 491/08 (2013.01); C07D 317/50 (2013.01); C07C 39/15 (2013.01); C07C 235/34 (2013.01); C07C 231/02 (2013.01); C07D 471/04 (2013.01); C07D 211/74 (2013.01); C07C 39/16 (2013.01); C07C 49/835 (2013.01); C07C 275/34 (2013.01); C07C 49/83 (2013.01); C07C 235/48 (2013.01); C07D 213/69 (2013.01); C07D 409/14 (2013.01); C07C 235/54 (2013.01); C07D 333/16 (2013.01); C07D 241/08 (2013.01); C07C 215/50 (2013.01); C07D 317/60 (2013.01); C07D 221/18 (2013.01); C07D 311/60 (2013.01); C07C 235/38 (2013.01); C07D 295/096 (2013.01); C07C 45/62 (2013.01); C07D 213/85 (2013.01); C07D 213/30 (2013.01); C07D 221/08 (2013.01);
Abstract
Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, especially Aβ amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.