The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2014

Filed:

Oct. 27, 2006
Applicants:

Oliver Von Stein, Upplands Väsby, SE;

Karin Hellström, Trosa, SE;

Inventors:

Oliver Von Stein, Upplands Väsby, SE;

Karin Hellström, Trosa, SE;

Assignee:

Index Pharmaceuticals AB, Stockholm, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 31/56 (2006.01); A61K 31/7088 (2006.01);
U.S. Cl.
CPC ...
A61K 31/56 (2013.01); A61K 31/7088 (2013.01);
Abstract

A method for enhancing the clinical responsiveness to an anti-inflammatory therapy in a patient afflicted with an inflammatory condition, comprising administering an oligonucleotide having the sequence 5'-Xm-CG-Yn-3′ in an effective amount to said patient, and wherein X is A, T, C or G; Y is A, T, C or G; m=1-40; n=1-40 and wherein at least one CG dinucleotide is unmethylated. The invention also encompasses the use of such an oligonucleotide for the manufacture of a medicament for enhancing steroid efficacy in the treatment of a patient afflicted with an inflammatory condition.


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