The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2014

Filed:

Aug. 05, 2010
Applicants:

Daniel Obrecht, Bättwil, CH;

Frank Otto Gombert, Basel, CH;

John Anthony Robinson, Wermatswil, CH;

Krystyna Patora-komisarska, Zürich, CH;

Inventors:

Daniel Obrecht, Bättwil, CH;

Frank Otto Gombert, Basel, CH;

John Anthony Robinson, Wermatswil, CH;

Krystyna Patora-Komisarska, Zürich, CH;

Assignees:

Polyphor AG, Allschwil, CH;

Universitat Zurich, Zurich, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 7/54 (2006.01); A01N 47/44 (2006.01); C07K 7/64 (2006.01);
U.S. Cl.
CPC ...
C07K 7/54 (2013.01); A01N 47/44 (2013.01); C07K 7/64 (2013.01);
Abstract

β-Hairpin peptidomimetics of the general formula Cyclo(-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-), enantiomers and pharmaceutically acceptable salts thereof, with Xaa-Xaabeing amino acid residues of certain types which are defined in the description and the claims, have anti-infective activity, e.g. to selectively inhibit the growth of or to kill microorganisms such asand/or. They can be used as medicaments to treat or prevent infections or as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials. These peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.


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