The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2014
Filed:
Dec. 15, 2011
Sei Kwang Hahn, Pohang, KR;
Choun-ki Joo, Seoul, KR;
Yoon Keun Kim, Pohang, KR;
Seung Kew Yoon, Seoul, KR;
Eun Ju OH, Busan, KR;
Ki Su Kim, Suwon, KR;
Hyemin Kim, Daegu, KR;
Kitae Park, Jeonju, KR;
Jeong-a Yang, Cheongju, KR;
Jun-sub Choi, Yongin, KR;
You ME Tae, Incheon, KR;
Wonhee Hur, Seoul, KR;
Sei Kwang Hahn, Pohang, KR;
Choun-Ki Joo, Seoul, KR;
Yoon Keun Kim, Pohang, KR;
Seung Kew Yoon, Seoul, KR;
Eun Ju Oh, Busan, KR;
Ki Su Kim, Suwon, KR;
Hyemin Kim, Daegu, KR;
Kitae Park, Jeonju, KR;
Jeong-A Yang, Cheongju, KR;
Jun-Sub Choi, Yongin, KR;
You Me Tae, Incheon, KR;
Wonhee Hur, Seoul, KR;
Postech Academy-Industry Foundation, Pohang, KR;
Abstract
The present invention relates to a drug delivery composition comprising a hyaluronic acid-peptide conjugate micelle and a production method thereof. According to the drug delivery composition and the production method of the drug-loaded, hyaluronic acid-peptide conjugate micelle of the present invention, the reaction for encapsulating can proceed in a mixed solvent of an aqueous solvent and an organic solvent. Therefore, the present invention can be applied to various types of water-insoluble active components and the biocompatible and biodegradable derivative can encapsulate a drug to provide a drug-loaded micelle, which is safe to be applied for human bodies. Moreover, the micelle has a therapeutic effect from the peptide contained therein, which can act in combination with the drug as packing therein. Therefore, the drug delivery composition and its production method can be utilized in the field of producing a sustained release formulation with an extended duration of the medicinal effect.