The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2014

Filed:

Dec. 15, 2010
Applicants:

Bruce Allan Hay, Niskayuna, NY (US);

Brian Christopher Bales, Niskayuna, NY (US);

Michael Todd Luttrell, Clifton Park, NY (US);

Binil Itty Ipe Kandapallil, Mechanicville, NY (US);

Inventors:

Bruce Allan Hay, Niskayuna, NY (US);

Brian Christopher Bales, Niskayuna, NY (US);

Michael Todd Luttrell, Clifton Park, NY (US);

Binil Itty Ipe Kandapallil, Mechanicville, NY (US);

Assignee:

General Electric Company, Niskayuna, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61B 5/055 (2006.01); B82Y 15/00 (2011.01); A61K 49/18 (2006.01); B82Y 30/00 (2011.01); B82Y 5/00 (2011.01); B82Y 40/00 (2011.01);
U.S. Cl.
CPC ...
A61K 49/1842 (2013.01); B82Y 15/00 (2013.01); A61K 49/1845 (2013.01); B82Y 30/00 (2013.01); B82Y 5/00 (2013.01); B82Y 40/00 (2013.01);
Abstract

A nanoparticle composition is provided, wherein the composition comprises a nanoparticulate metal oxide; and a phosphorylated polyol comprising at least two phosphate groups. The polyol comprises one or more hydrophilic groups selected from the group consisting of polyethylene ether moieties, polypropylene ether moieties, polybutylene ether moieties, and combinations of two or more of the foregoing hydrophilic moieties. A method of making the nanoparticle composition is also provided. The nanoparticle compositions provided by the present invention may be used as contrast agents in medical imaging techniques such as X-ray and magnetic resonance imaging.


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