The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2014
Filed:
Oct. 29, 2009
Jay Gregory Calvert, Otsego, MI (US);
Michael G. Sheppard, Elthan, AU;
Siao-kun W. Welch, Kalamazoo, MI (US);
Raymond R. R. Rowland, Manhattan, KS (US);
Dal-young Kim, Manhattan, KS (US);
Jay Gregory Calvert, Otsego, MI (US);
Michael G. Sheppard, Elthan, AU;
Siao-Kun W. Welch, Kalamazoo, MI (US);
Raymond R. R. Rowland, Manhattan, KS (US);
Dal-Young Kim, Manhattan, KS (US);
Zoetis LLC, Florham Park, NJ (US);
Abstract
The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, wherein the polynucleotide molecule lacks at least one detectable antigenic epitope of North American PRRS virus. The invention also provides vaccines comprising genetically modified North American PRRS virus, RNA molecules, plasmids and viral vectors comprising the isolated polynucleotide molecules. Also provided are isolated polynucleotide molecules further comprising at least one nucleotide sequence that encodes a detectable heterologous antigenic epitope, and vaccines comprising North American PRRS virus, RNA molecules, plasmids and viral vectors comprising such isolated polynucleotide molecules.