The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2014
Filed:
Feb. 19, 2009
Fabiana Fernandez, Unterengstringen, CH;
Michael Wetter, Zurich, CH;
Michael Kowarik, Zurich, CH;
Michael Wacker, Unterengstringen, CH;
Fabiana Fernandez, Unterengstringen, CH;
Michael Wetter, Zurich, CH;
Michael Kowarik, Zurich, CH;
Michael Wacker, Unterengstringen, CH;
Glycovaxyn AG, Schlieren, CH;
Abstract
The present invention is directed to a bioconjugate vaccine, such as an O1-bioconjugate vaccine, comprising: a protein carrier comprising a protein carrier containing at least one consensus sequence, D/E-X-N-Z-S/T, wherein X and Z may be any natural amino acid except proline; at least one antigenic polysaccharide from at least one pathogenic bacterium, linked to the protein carrier; and, optionally, an adjuvant. In another aspect, the present invention is directed to a method of producing an O1-bioconjugate in a bioreactor comprising a number steps.