The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2014

Filed:

Feb. 06, 2013
Applicant:

Medimmune Limited, Cambridge, GB;

Inventors:

Julie Rinkenberger, Moraga, CA (US);

Ian Foltz, British Columbia, CA;

Avril Alfred, British Columbia, CA;

Simon Thomas Barry, Macclesfield, GB;

Vahe Bedian, Waltham, MA (US);

Assignee:

MedImmune Limited, Cambridge, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2839 (2013.01); C07K 2317/565 (2013.01); C07K 2317/56 (2013.01); C07K 2316/96 (2013.01); C07K 2317/567 (2013.01); C07K 2317/92 (2013.01); C07K 2317/21 (2013.01);
Abstract

Targeted binding agents, such antibodies directed to the antigen αVβ6 and uses of such agents are described. In particular, fully human monoclonal antibodies directed to the antigen αVβ6 are disclosed. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3 are disclosed. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also disclosed.


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