The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2014

Filed:

Nov. 06, 2012
Applicant:

Janssen Biotech, Inc., Horsham, PA (US);

Inventors:

Jill Giles-Komar, Spring House, PA (US);

George Heavner, Merrimack, NH (US);

David Knight, Berwyn, PA (US);

Jinquan Luo, Spring House, PA (US);

David Peritt, Lake Forest, IL (US);

Bernard Scallon, Spring House, PA (US);

David Shealy, Spring House, PA (US);

Assignee:

Janssen Biotech, Inc., Horsham, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/24 (2006.01); A61K 31/56 (2006.01); A61K 51/00 (2006.01); A61K 31/137 (2006.01); C07K 14/54 (2006.01); A61K 38/27 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/244 (2013.01); C07K 2317/55 (2013.01); A61K 31/56 (2013.01); C07K 2316/96 (2013.01); A61K 51/00 (2013.01); C07K 2317/21 (2013.01); A61K 31/137 (2013.01); A61K 2039/505 (2013.01); C07K 14/54 (2013.01); A61K 38/27 (2013.01); A61K 45/06 (2013.01); A61K 39/3955 (2013.01); C07K 2317/34 (2013.01); C07K 14/5434 (2013.01);
Abstract

An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of residues 15, 17-21, 23, 40-43, 45-47, 54-56 and 58-62 of the amino acid sequence of the p40 subunit of IL-12, including isolated nucleic acids that encode at least one anti-IL-12 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in treating IL-12-related disorders, such as psoriatic arthritis.


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