The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2014

Filed:

Mar. 13, 2013
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Ny Sin, East Hampton, CT (US);

Zheng Liu, Beacon Falls, CT (US);

Jacob Swidorski, Southington, CT (US);

Sing-Yuen Sit, Meriden, CT (US);

Jie Chen, Madison, CT (US);

Yan Chen, Wallingford, CT (US);

Nicholas A. Meanwell, East Hampton, CT (US);

Alicia Regueiro-Ren, Middletown, CT (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J 53/00 (2006.01); C07D 498/08 (2006.01); C07D 495/08 (2006.01); C07D 495/10 (2006.01); C07D 487/10 (2006.01); C07J 63/00 (2006.01); C07D 491/08 (2006.01); C07D 209/52 (2006.01); C07D 487/08 (2006.01);
U.S. Cl.
CPC ...
C07D 487/08 (2013.01); C07D 498/08 (2013.01); C07D 495/08 (2013.01); C07D 495/10 (2013.01); C07D 487/10 (2013.01); C07J 63/008 (2013.01); C07D 491/08 (2013.01); C07D 209/52 (2013.01);
Abstract

Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-17 bicyclic amines of triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III: These compounds are useful for the treatment of HIV and AIDS.


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