The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2014
Filed:
Jul. 05, 2012
Applicants:
William E. Delaney, Iv, Foster City, CA (US);
Guofeng Cheng, Foster City, CA (US);
Hongmei MO, Palo Alto, CA (US);
Simin Xu, Palo Alto, CA (US);
Betty Peng, San Mateo, CA (US);
Inventors:
William E. Delaney, IV, Foster City, CA (US);
Guofeng Cheng, Foster City, CA (US);
Hongmei Mo, Palo Alto, CA (US);
Simin Xu, Palo Alto, CA (US);
Betty Peng, San Mateo, CA (US);
Assignee:
Gilead Sciences, Inc., Foster City, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); C12Q 1/66 (2006.01); C12N 15/86 (2006.01); C12N 5/10 (2006.01); C12N 5/071 (2010.01); C07K 14/005 (2006.01); G01N 33/576 (2006.01); C12Q 1/68 (2006.01); C12N 15/64 (2006.01); C12N 15/65 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C07K 14/005 (2013.01); C12N 2770/24231 (2013.01); G01N 33/5767 (2013.01); C12N 2770/24222 (2013.01); G01N 2333/186 (2013.01); C12N 2770/24243 (2013.01);
Abstract
Replicons of genotype 4 hepatitis C virus (HCV) are provided. These replicons contains adaptive mutations giving rise to the HCV's capability to replicate in vitro. Methods of preparing genotype 4 replicons and methods of using these replicons to screen antiviral agents are also provided.