IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8889730 B1

PDFFull Text
Date of Patent:
Nov. 18, 2014

Filed:

Mar. 15, 2013

Indole and indazole compounds that activate ampk

Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Samit Bhattacharya, Waltham, MA (US);

Kimberly Cameron, Cambridge, MA (US);

Matthew Dowling, Groton, CT (US);

Dilinie Fernando, Niantic, CT (US);

David Ebner, Somerville, MA (US);

Kevin Filipski, Reading, MA (US);

Daniel Kung, Salem, CT (US);

Esther Lee, Shirley, MA (US);

Aaron Smith, Providence, RI (US);

Meihua Tu, Acton, MA (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:

James T. Wasicak

Primary Examiner:

Sreeni Padmanabhan

Assistant Examiner:

Irina Neagu

Int. Cl.
CPC ...
A61K 31/404 (2006.01); C07D 209/42 (2006.01); A61P 13/12 (2006.01); A61P 3/10 (2006.01); C07D 403/12 (2006.01); C07D 401/04 (2006.01); A61K 31/416 (2006.01); C07D 413/14 (2006.01); C07D 405/14 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 231/56 (2006.01); C07D 413/12 (2006.01); C07D 401/14 (2006.01); C07D 401/10 (2006.01);
U.S. Cl.
CPC ...
C07D 231/56 (2013.01); C07D 403/12 (2013.01); C07D 401/04 (2013.01); A61K 31/416 (2013.01); C07D 209/42 (2013.01); A61K 31/404 (2013.01); C07D 413/14 (2013.01); C07D 405/14 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 413/12 (2013.01); C07D 401/14 (2013.01); C07D 401/10 (2013.01);
Abstract

The present invention relates to indole and indazole compounds of Formula (I) that activate 5' adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, or disorders ameliorated by activation of AMPK.

Find Patent Forward Citations

Loading…