The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2014

Filed:

Feb. 24, 2012
Applicants:

James F. Blake, Boulder, CO (US);

Robert Kirk Delisle, Longmont, CO (US);

Lisa A. DE Meese, Phoenix, AZ (US);

James M. Graham, Longmont, CO (US);

Yvan Le Huerou, Boulder, CO (US);

Michael Lyon, Eris, CO (US);

John E. Robinson, Boulder, CO (US);

Eli M. Wallace, Richardson, TX (US);

Bin Wang, Dallas, TX (US);

Rui Xu, Boulder, CO (US);

Inventors:

James F. Blake, Boulder, CO (US);

Robert Kirk Delisle, Longmont, CO (US);

Lisa A. De Meese, Phoenix, AZ (US);

James M. Graham, Longmont, CO (US);

Yvan Le Huerou, Boulder, CO (US);

Michael Lyon, Eris, CO (US);

John E. Robinson, Boulder, CO (US);

Eli M. Wallace, Richardson, TX (US);

Bin Wang, Dallas, TX (US);

Rui Xu, Boulder, CO (US);

Assignee:

Array BioPharma Inc., Boulder, CO (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 487/10 (2006.01); C07D 491/048 (2006.01); C07D 401/06 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 491/048 (2013.01); C07D 487/10 (2013.01); C07D 401/06 (2013.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract

Compounds of Formula I: in which R, R, R, Rand Rhave the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by PIM-1 and/or PIM-2 and/or PIM-3 kinases.


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