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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8889691 B1

PDFFull Text
Date of Patent:
Nov. 18, 2014

Filed:

Sep. 23, 2013

Indole compounds as an inhibitor of cellular necrosis

Applicant:

Lg Life Sciences Ltd., Seoul, KR;

Inventors:

Soon Ha Kim, Daejeon, KR;

Hyoung Jin Kim, Daejeon, KR;

Sun Young Koo, Daejeon, KR;

Sung Bae Lee, Daejeon, KR;

Heui Sul Park, Daejeon, KR;

Seung Hyun Yoon, Daejeon, KR;

Seung Yup Paek, Daejeon, KR;

Hyo Shin Kwak, Daejeon, KR;

Dong Ook Seo, Daejeon, KR;

Eok Park, Daejeon, KR;

Assignee:

LG Life Sciences Ltd., Seoul, KR;

Attorney:

Birch, Stewart, Kolasch & Birch, LLP

Primary Examiner:

Robert Havlin

Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/541 (2006.01); C07D 413/14 (2006.01); A61K 31/445 (2006.01); A61K 31/4439 (2006.01); A61K 45/06 (2006.01); A61K 31/4545 (2006.01); A61K 31/427 (2006.01); C07D 417/14 (2006.01); A61K 31/5377 (2006.01); C07F 9/6558 (2006.01); C07D 487/04 (2006.01); A61K 31/404 (2006.01); C07D 413/04 (2006.01); A61K 31/675 (2006.01); A61K 31/416 (2006.01); A61K 31/454 (2006.01); C07D 417/06 (2006.01); A61K 31/497 (2006.01); C07D 417/04 (2006.01);
U.S. Cl.
CPC ...
C07D 417/06 (2013.01); A61K 31/541 (2013.01); C07D 413/14 (2013.01); A61K 31/496 (2013.01); A61K 31/445 (2013.01); A61K 31/4439 (2013.01); A61K 45/06 (2013.01); A61K 31/4545 (2013.01); A61K 31/427 (2013.01); C07D 417/14 (2013.01); A61K 31/5377 (2013.01); C07F 9/65583 (2013.01); C07D 487/04 (2013.01); A61K 31/404 (2013.01); C07D 413/04 (2013.01); C07F 9/65586 (2013.01); A61K 31/675 (2013.01); A61K 31/416 (2013.01); A61K 31/454 (2013.01); A61K 31/497 (2013.01); C07D 417/04 (2013.01);
Abstract

The present invention relates to new indole compounds, pharmaceutically acceptable salts or isomers thereof which are useful for the prevention or treatment of cellular necrosis and necrosis-associated diseases. The present invention also relates to a method and a composition for the prevention or treatment of cellular necrosis and necrosis-associated diseases, comprising said indole compounds as an active ingredient.

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