The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2014

Filed:

Sep. 23, 2011
Applicants:

Clifford Cheng, Cambridge, MA (US);

Gerald W. Shipps, Jr., Stoneham, MA (US);

Xiaohua Huang, Brookline, MA (US);

Ying Huang, Berkeley Heights, NJ (US);

Ning Shao, Watchung, NJ (US);

Ashwin Rao, Morganville, NJ (US);

Anandan Palani, Bridgewater, NJ (US);

Peter Orth, New York, NY (US);

Johannes H. Voigt, Cranford, NJ (US);

Robert J. Herr, Voorheesville, NY (US);

Lana Michele Rossiter, Clifton Park, NY (US);

Qi Zeng, Delmar, NY (US);

Xianfeng Sun, Guilderland, NY (US);

Inventors:

Clifford Cheng, Cambridge, MA (US);

Gerald W. Shipps, Jr., Stoneham, MA (US);

Xiaohua Huang, Brookline, MA (US);

Ying Huang, Berkeley Heights, NJ (US);

Ning Shao, Watchung, NJ (US);

Ashwin Rao, Morganville, NJ (US);

Anandan Palani, Bridgewater, NJ (US);

Peter Orth, New York, NY (US);

Johannes H. Voigt, Cranford, NJ (US);

Robert J. Herr, Voorheesville, NY (US);

Lana Michele Rossiter, Clifton Park, NY (US);

Qi Zeng, Delmar, NY (US);

Xianfeng Sun, Guilderland, NY (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/498 (2006.01); C07D 241/44 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 413/06 (2006.01); C07D 401/06 (2006.01); C07D 403/12 (2006.01); C07D 403/06 (2006.01);
U.S. Cl.
CPC ...
C07D 403/06 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 413/06 (2013.01); C07D 241/44 (2013.01); C07D 401/06 (2013.01); C07D 403/12 (2013.01);
Abstract

The present invention relates to novel quinoxaline compounds of Formula I: as Fatty Acid Binding Protein ('FABP') inhibitors, pharmaceutical compositions comprising the quinoxaline compounds and the use of the quinoxaline compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose.


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