The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2014

Filed:

Sep. 30, 2009
Applicants:

James R. Baker, Jr., Ann Arbor, MI (US);

Xue-min Cheng, Ann Arbor, MI (US);

Abraham F. L. Van Der Spek, Ann Arbor, MI (US);

Baohua Mark Huang, Ann Arbor, MI (US);

Thommey P. Thomas, Dexter, MI (US);

Inventors:

James R. Baker, Jr., Ann Arbor, MI (US);

Xue-min Cheng, Ann Arbor, MI (US);

Abraham F. L. Van Der Spek, Ann Arbor, MI (US);

Baohua Mark Huang, Ann Arbor, MI (US);

Thommey P. Thomas, Dexter, MI (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5513 (2006.01); A61K 31/485 (2006.01); A61K 31/5377 (2006.01); C07D 489/02 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 47/483 (2013.01); A61K 47/48207 (2013.01); A61K 31/485 (2013.01);
Abstract

The present invention relates to novel therapeutic and diagnostic dendrimers. In particular, the present invention is directed to dendrimer-linker conjugates, methods of synthesizing the same, compositions comprising the conjugates, as well as systems and methods utilizing the conjugates (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease (e.g., cancer) diagnosis and/or therapy, pain therapy, etc.)). Accordingly, dendrimer-linker conjugates of the present invention may further comprise one or more components for targeting, imaging, sensing, and/or providing a therapeutic or diagnostic material and/or monitoring response to therapy.


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